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. 2021 Jul 16;36(1):189–196. doi: 10.1038/s41375-021-01345-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Among the 7 patients who were excluded from the study during screening, 2 failed in preculture, 1 had negative expression of both CD19 and CD20 by immunohistochemistry, and 4 had disease progression while waiting for hospitalisation. Among the 92 enroled patients, one patient failed leukapheresis, and another had AEs after leukapheresis. Before infusion, 1 patient had serious AEs, and 2 could not tolerate pretreatment due to disease progression. AEs adverse events.