Figure 5.

Modelling the effect of eccentricity and light exposure on ICPSER cell number. (A) ICPSER cell counts on retina regions of (3) monkeys’ eyes. (B) Scatterplot of observations in section A and predictions of a Bayesian Poisson regression model. The relative error was calculated as the average of the absolute relative differences. (C) The posterior distribution of the model predictions was used to assess the significance of the effect of light exposure and retina region on ICPSER cell counts. Differences were considered significant when P{ Pred_i > Pred_j | H } > 0.95, which denotes the posterior probability of the difference between predicted counts in experimental conditions i y j with H being the dataset of ICPSER cell counts used to fit the model; (D) Bayesian inference indicated that ICPSER cells are significantly more abundant in the peripheral and para/perifoveal retina than in fovea and that their number in the fovea and para/perifoveal region increases significantly after light exposure.