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IL-38 mediated attenuation of Th17 Cell Pathogenicity during EAU. (A, B) The proportion of GM-CSF+ IL-17A+ cells (gated on CD4+ cells) in EAU mice and IL-38-treated mice (n = 6). (C-H) The proportion of GM-CSF+ C to D, IL-23R+ E and F, and IL-10+ G and H cells on the gate of Th17 cells (CD4+IL-17A+ cells) in EAU mice and IL-38-treated mice (n = 6). Data shown as mean ± SD from three independent experiments. Data were analyzed using unpaired two-tailed Student t-tests, ****P < 0.0001.
