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. 2021 Nov 13;44(1):29–38. doi: 10.1007/s13258-021-01152-6

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — FOSL2 knockdown could promote the cell apoptosis and inflammasome activation. A and B The cell apoptosis was detected by flow cytometry and TUNEL staining (C). D The secretion of IL-1β and IL-18 were detected by ELISA assay, and the LDH activity in cell supernatant was detected by LDH release assay kit. E The expression of ASC, pro-caspase-1, caspase-1pro-IL-1β, IL-1β, pro-IL-18 and IL-18 were analyzed by western blot. *P < 0.05, **P < 0.01 vs. control group