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. 2021 Oct 27;126(1):109–119. doi: 10.1038/s41416-021-01579-4

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© The Author(s) 2021

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Fig. 2 — a, b The binding of the KLF5, BRD4, MED1 and RAD21 proteins to the KLF5 promoter and enhancer in HT29 (a) and SW48 (b) cell lines analysed by ChIP-qPCR. Fold enrichment normalised to the value of the IgG control is shown. *P < 0.01. c Expression level of KLF5 mRNA in HT29 cells transfected with siRNAs against BRD4, MED1 and RAD21. The relative value is calculated by the expression level of the si-negative control transfected cells (siNC). *P < 0.01.