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. 2021 Nov 1;126(1):100–108. doi: 10.1038/s41416-021-01607-3

Fig. 1. TIM3+ cells are densely infiltrated in gastric cancer tissues and associated with disease progression.

Fig. 1

a Flow diagram for characterisation of three cohorts involved in this study. b Representative images of immunohistochemistry (IHC) for TIM3+ cells (left and median panel) and haematoxylin–eosin (H&E) staining (right panel) in gastric tissues. Arrowheads show TIM3+ cells. c Comparison of TIM3+ cell infiltration between intratumoural (n = 436) and peritumoural (n = 436) gastric tissues based on IHC evaluation. Paired t test. d Boxplots display the association between intratumoural TIM3+ cell infiltration and TNM stage. Kruskal–Wallis test. P values less than 0.05 were shown in bold.