Table 2.

Multivariable Regression of Hourly Neurocheck Order Discontinuation.

Variable	Multivariable hazard ratio (95% CI)a	P valueb
Age
18 to 64 years old	REF
65 to 79 years old	0.97 (0.92, 1.02)	0.193
80 years or older	1.19 (1.11, 1.26)	<0.001
Admission diagnosis category
None listed	REF
Coma and increased ICP	0.76 (0.66, 0.88)	<0.001
Traumatic non-TBI	1.03 (0.90, 1.20)	0.617
Ischemic stroke	1.01 (0.87, 1.17)	0.931
Non-neurological	1.04 (0.90, 1.21)	0.565
CNS tumor	1.64 (1.41, 1.91)	<0.001
TBI	0.91 (0.78, 1.05)	0.211
Other neurological	1.58 (1.32, 1.87)	<0.001
Elective vascular	1.59 (1.30, 1.92)	<0.001
Spine and SCI	0.81 (0.67, 0.98)	0.032
Seizure	1.47 (1.19, 1.80)	<0.001
Intracranial hemorrhage	0.89 (0.73, 1.10)	0.285
Subarachnoid hemorrhage	0.54 (0.42, 0.69)	<0.001
Ordering service
Neurocritical care	REF
Neurosurgery	1.49 (1.37, 1.61)	<0.001
Trauma	1.52 (1.42, 1.65)	<0.001
Non-neuro ICU	1.03 (0.93, 1.14)	0.536
Non-ICU/other	1.39 (1.27, 1.51)	<0.001
Year
2012	REF
2013	1.15 (1.06, 1.25)	0.001
2014	1.19 (1.02, 1.39)	0.027
2015	1.20 (0.03, 1.40)	0.022
2016	1.17 (0.99, 1.36)	0.052
2017	1.20 (1.03, 1.40)	0.018
2018	1.44 (1.20, 1.73)	<0.001
Quarter
January to March	REF
April to June	1.00 (0.94, 1.07)	0.900
July to September	1.00 (0.94, 1.06)	0.981
October to December	1.02 (0.95, 1.08)	0.628

^aHigher hazard ratio (HR) represents faster hourly neurocheck discontinuation.

^bCalculated using multivariable Cox regression.