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. 2021 Apr 6;11(12):3889–3907. doi: 10.1016/j.apsb.2021.03.042

Figure 12.

Figure 12

Structures of novel linker‒antibody attachments. (A) “Re-bridge” strategy and the structure of BVP conjugation-containing ADCs. Adapted with modification from Ref. 71 © 2020 Elsevier. (B) The structure of N-methyl-N-phenylvinylsulfonamides attachment-containing ADCs. Adapted with modification from Ref. 73 © 2018 American Chemical Society. (C) The structure and synthesis of Lx® attachment-containing ADCs. Adapted with modification from Ref. 75 © 2016 American Association for Cancer Research.