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Structures of cathepsin-cleavable triggers. (A) The structure of the cBu-Cit-PABC-containing ADCs. Adapted with modification from Ref. 19 © 2017 American Association for Cancer Research. (B) The structure of CX-containing ADCs and catabolites expected from lysosomal proteolysis. Adapted with modification from Ref. 21 © 2016 American Association for Cancer Research.
