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IC50 values of the inhibitors and their combination against B16F10 cells
| Sl. No. | Inhibitor | IC50 values (µM) |
|---|---|---|
|
| ||
| B16F10 | ||
| 1 | U0126 | 25.29±1.4 |
| 2 | LY294002 | 16.43±1.2 |
| 3 | U0126 + LY294002 | 10.19±1.0 |
B16F10 is mouse melanoma cell line. Drug combination is U0126 (10 µM) + LY294002 (10 µM). IC50 - Concentration of compound required for 50% inhibition of cell viability determined using MTT assay. The results represent the mean ± standard deviations of three repeats.
