Table 2.

Altered proteins in B16F10R cells as compared to the B16F10C cells

Sl. no.	Gene Symbol	Description	Fold increase	Sl. no.	Gene Symbol	Description	Fold decrease
1	Mt1	Metallothionein-1	4.52	1	Tpm2	Tropomyosin beta chain isoform Tpm2.2st	0.25
2	Garnl3	GTPase-activating Rap/Ran-GAP domain-like protein 3 isoform X1	3.76	2	Tmprss13	Transmembrane protease serine 13 isoform X1	0.29
3	Ak1	Adenylate kinase isoenzyme 1 isoform 1	3.41	3	Ptma	Prothymosin alpha	0.30
4	C4b	Complement C4-B isoform X1	3.32	4	Sfr1	Swi5-dependent recombination DNA repair protein 1 homolog	0.31
5	Adh7	Alcohol dehydrogenase class 4 mu/sigma chain	3.28	5	Fdps	Farnesyl pyrophosphate synthase isoform 1 precursor	0.34
6	Lcorl	Ligand-dependent nuclear receptor corepressor-like protein isoform X1	3.20	6	Lipa	Lysosomal acid lipase/cholesteryl ester hydrolase precursor	0.36
7	Des	Desmin	3.12	7	Irak4	Interleukin-1 receptor-associated kinase 4	0.37
8	Mt2	Metallothionein-2	3.06	8	Espn	Espin isoform X1	0.37
9	Gripap1	GRIP1-associated protein 1 isoform X1	3.02	9	Tcea1	Transcription elongation factor A protein 1 isoform 3	0.37
10	C7	Complement component C7 precursor	2.95	10	Ndufab1	Acyl carrier protein, mitochondrial isoform X1	0.38

The data obtained for LC-MS/MS was analyzed using Proteome discoverer 2.1, which compares the LC-MS/MS data against mouse database. Altered proteins include both increased and decreased proteins. This table shows 10 proteins with highest fold increase and 10 proteins with highest fold decrease, their gene symbol, and their fold change, i.e., concentration in B16F10R cells/concentration in B16F10C cells.