Table 3.
Categorization of the phosphoproteins altered in B16F10R cells based on the pathways they are associated with
| Sl. No. | KEGG Pathway | Protein count | Name of the protein |
|---|---|---|---|
| 1 | Spliceosome | 11 | Ddx46, Rbm17, Rbm8a, SNW1, U2surp, Acin1, Srsf1, Srsf4, Snrnp70, Tra2a, Tra2b |
| 2 | RNA transport | 11 | Rbm8a, Thoc5, Acin1, Casc3, Eif3b, Eif4g1, Eif4b, Eif5b, Pnn, Rnps1, Srrm1 |
| 3 | mRNA surveillance pathway | 7 | Fip1l1, Rbm8a, Acin1, Casc3, Pnn, Rnps1, Srrm1 |
| 4 | Protein processing in endoplasmic reticulum | 5 | Dnaja2, Nsfl1c, Sec61b, Canx, Rrbp1 |
| 5 | Cell cycle | 4 | Cdk2, HDAC2, Mcm2, Smc3 |
DAVID Functional Annotation Chart software was used for the categorization of the altered phosphoproteins into various cellular pathways. KEGG: Kyoto Encyclopedia of Genes and Genomes is bioinformatics software for associating genomes to metabolism.