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The concentration of each drug needed to kill half of the cells. Images of MCF7 MTT assay plates (A, B) and corresponding IC50 curves generated in GraphPad Prism (C). MCF7 cells were least sensitive to carboplatin and cisplatin and most sensitive to oxaliplatin, doxorubicin, and paclitaxel. The IC50 concentrations were used for treatment of cells for cytokine profiling. IC50 concentrations for HCT116 cells were measured using a CellTiterGlo assay (D).
