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. 2021 Dec 22;12:731483. doi: 10.3389/fphar.2021.731483

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Copyright © 2021 Shawki, Saad, Rahmo, Wadie and El-Abhar.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of Lira on protein expression of striatal (A) p-PI3K, (B) p-Akt, (C) p-GSK-3β, and (D) p-β-catenin in 3-NP-treated rats. Data are presented as mean ± S.D. (n = 3/group). Statistical analysis was performed using one-way ANOVA followed by Tukey’s multiple comparison test; as compared with (*) NC, (#) 3-NP, and (@) NC + Lira groups, p < 0.05. ANOVA, analysis of variance; p-Akt, phosphor-protein kinase B; p-GSK-3β, phosphor=glycogen synthase kinase; Lira, liraglutide; NC, normal control; 3-NP, 3-nitropropionic acid; p-PI3K. phospho-phosphoinositide 3-kinase.