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. 2021 Dec 22;12:731483. doi: 10.3389/fphar.2021.731483

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Copyright © 2021 Shawki, Saad, Rahmo, Wadie and El-Abhar.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of Lira on mRNA expression of striatal (A) PBR, (B) HSP27, (C) GFAP, and (D) DARPP-32 in 3-NP-treated rats. Data are presented as mean ± S.D. (n = 3/group). Statistical analysis was performed using one-way ANOVA followed by Tukey’s multiple comparison test; compared with (*) NC, (#) 3-NP, and (@) NC + Lira groups, p < 0.05. ANOVA, analysis of variance; DARPP-32, dopamine- and cAMP-regulated phosphoprotein; GFAP, glial fibrillary acidic protein; HSP27, heat shock protein 27; Lira, liraglutide; NC, normal control; 3-NP, 3-nitropropionic acid; PBR, peripheral benzodiazepine receptor.