Table 2.

Kidney histopathological scoring of healthy and NASH rats receiving either CDDP or vehicle.

Disease	Drug	Total	Degeneration	Necrosis	Apoptosis	Inflammation	Hyalin casts
Control	Naïve	0.50 ± 1.22	0.33 ± 0.82	0	0	0.17 ± 0.41	0
	CDDP	13.33 ± 1.51	3.17 ± 0.75	4.00 ± 0.89	1.17 ± 0.41	2.17 ± 0.41	2.83 ± 0.75
NASH	Naïve	0	0	0	0	0	0
	CDDP	10.60 ± 3.29	3.80 ± 1.64	2.40 ± 0.55	1.40 ± 0.55	0.80 ± 0.84	2.20 ± 0.84
Two-way ANOVA	Diet	∗	ns	∗∗	ns	∗∗	ns
	Drug	∗∗∗∗	∗∗∗∗	∗∗∗∗	∗∗∗∗	∗∗∗∗	∗∗∗∗

Mean scores represent n = 6 rats/group with the total being the average of the sum of all scores.

Means were compared by two-way analysis of variance where P < 0.05 (∗), <0.01 (∗∗), <0.001 (∗∗∗), <0.0001 (∗∗∗∗).