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JOSD2 shows high correlation with YAP in CCA patients. (A) and (B) Immunohistochemical staining of YAP and JOSD2 in CCA microarray (n = 54/group). (C) JOSD2 and YAP expression levels were positively correlated in CCA tumor samples; n = 54, r = 0.718, P < 0.01. (D) Scheme for the regulatory mechanism of JOSD2 on YAP/TAZ in CCA malignant proliferation.
