Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 8;11(12):3756–3767. doi: 10.1016/j.apsb.2021.09.002

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

VC sensitizes hepatocytes to cell death. (A) Representative photomicrographs are shown for hepatocytes isolated from animals exposed in vivo to LFD ± VC for 12 weeks. These hepatocytes were then challenged with ± CAA ex vivo. Cellomics images for TMRM (mitochondrial membrane potential), TOTO-3 (cell death), and Hoechst (nuclear) fluorescent staining are shown. (B) 2D scatter plots of cellomics image analysis for LFD ± VC ± CAA in which TMRM is depicted as a function of TOTO-3. Thresholds were calculated for positive and negative fluorescence of each marker. (C) Relative percentage of cells in each quadrant (of cellomics analysis in B) are shown. Samples size per group n = 8–10.