Table 1.
List of most upregulated detoxification genes in FUMOZ strain
| Gene ID | P | FC | Log FC | Gene symbol | FUMOZ reads | FANG reads | Description |
|---|---|---|---|---|---|---|---|
| Cytochrome P450 | |||||||
| AFUN015792 | 0.0005 | 78.0 | 6.3 | CYP6P9a | 84,176.5 | 822.6 | Cytochrome P450 |
| AFUN015889 | 0.0015 | 11.1 | 3.5 | CYP6P9b | 11,906.6 | 744.2 | Cytochrome P450 |
| AFUN020895 | 0.0065 | 5.9 | 2.6 | CYP6P4a | 1,895.4 | 255.5 | Cytochrome P450 |
| AFUN019523 | 0.0466 | 4.9 | 2.3 | CYP325J1 | 19.6 | 3.4 | Cytochrome P450 |
| AFUN006135 | 0.0049 | 3.0 | 1.6 | CYP4C36 | 987.1 | 261.9 | Cytochrome P450 |
| AFUN019401 | 0.0407 | 2.9 | 1.5 | CYP6M4 | 2,115.5 | 731.1 | Cytochrome P450 |
| AFUN021097 | 0.0491 | 2.5 | 1.3 | CYP4H24 | 2,613.8 | 1,057.2 | Cytochrome P450 |
| AFUN015938 | 0.0042 | 2.5 | 1.3 | CYP9M1 | 1,962.9 | 585.2 | Cytochrome P450 |
| AFUN007549 | 0.0018 | 2.4 | 1.3 | CYP9K1 | 3,991.8 | 1,049.2 | Cytochrome P450 |
| AFUN015785 | 0.0076 | 2.1 | 1.1 | CYP6AA2 | 776.2 | 254.4 | Cytochrome P450 |
| AFUN015801 | 0.0015 | 2.1 | 1.1 | CYP6P2 | 2,106.3 | 718.8 | Cytochrome P450 |
| AFUN002978 | 0.0073 | 2.1 | 1.0 | CYP314A1 | 642.4 | 219.3 | Cytochrome P450 |
| Glutathione S-transferases (GSTs) | |||||||
| AFUN022201 | 0.0081 | 11.8 | 3.6 | AFUN022201 | 54.3 | 5.0 | Glutathione peroxidase |
| AFUN016008 | 0.0072 | 4.0 | 2.0 | GSTE6 | 605.7 | 125.5 | Glutathione S-transferase |
| AFUN015808 | 0.0038 | 3.6 | 1.8 | GSTE3 | 3,351.1 | 772.5 | Glutathione S-transferase |
| AFUN015809 | 0.0013 | 3.3 | 1.7 | GSTE2 | 2,415.9 | 491.8 | Glutathione S-transferase |
| AFUN015839 | 0.0034 | 3.1 | 1.6 | GSTD3 | 1,298.3 | 332.6 | Glutathione S-transferase |
| AFUN015811 | 0.0032 | 2.5 | 1.3 | GSTE5 | 1,185.9 | 332.4 | Glutathione S-transferase |
| AFUN016010 | 0.0031 | 2.4 | 1.3 | GSTD1 | 13,199.4 | 4,246.1 | Glutathione S-transferase |
| AFUN007291 | 0.0217 | 2.4 | 1.2 | GSTT2 | 660.4 | 238.0 | Glutathione S-transferase |
| Carboxylesterases | |||||||
| AFUN016265 | 0.0177 | 7.2 | 2.9 | AFUN016265 | 387.8 | 51.8 | Carboxylesterase |
| AFUN016264 | 0.0119 | 2.4 | 1.3 | AFUN016264 | 240.6 | 73.6 | Carboxylesterase |
| AFUN000374 | 0.0037 | 2.2 | 1.2 | AFUN000374 | 2,557.4 | 846.9 | Carboxylesterase |
| Other detox genes | |||||||
| AFUN004354 | 0.0103 | 2.1 | 1.1 | AFUN004354 | 1,005.3 | 317.5 | UDP-glucuronosyltransferase |
| AFUN020670 | 0.0041 | 2.4 | 1.3 | AFUN020670 | 995.7 | 247.5 | Xanthine dehydrogenase |
| AFUN008239 | 0.0149 | 2.7 | 1.5 | AFUN008239 | 830.9 | 225.8 | Sulfotransferase |
| AFUN016207 | 0.0047 | 4.6 | 2.2 | AFUN016207 | 699.0 | 162.8 | Sulfotransferase |
| AFUN016205 | 0.0246 | 2.8 | 1.5 | AFUN016205 | 1,290.1 | 398.8 | Sulfotransferase |
| AFUN016210 | 0.0054 | 2.4 | 1.3 | AFUN016210 | 297.2 | 91.2 | Sulfotransferase |
| Transporters | |||||||
| AFUN019220 | 0.0020 | 4.7 | 2.2 | AFUN019220 | 4,442.5 | 676.7 | ATP-binding cassette transporter |
| AFUN016412 | 0.0105 | 2.5 | 1.3 | AFUN016412 | 5,425.0 | 1,795.5 | Solute carrier family 15 member |
| AFUN000622 | 0.0099 | 3.8 | 1.9 | AFUN000622 | 1,350.9 | 235.3 | Solute carrier family 23 ( |
| AFUN015826 | 0.0013 | 2.1 | 1.0 | AFUN015826 | 1,479.5 | 496.5 | Solute carrier family 7 |
| AFUN021547 | 0.0087 | 2.8 | 1.5 | AFUN021547 | 513.9 | 144.3 | Sugar transporter SWEET |
| AFUN021546 | 0.0200 | 3.1 | 1.6 | AFUN021546 | 1,490.9 | 362.5 | Sugar transporter SWEET1 |
| Mitochondrial/redox | |||||||
| AFUN010502 | 0.0007 | 8.2 | 3.0 | AFUN010502 | 4,959.9 | 534.9 | ATP synthase subunit d, mitochondrial |
| AFUN011500 | 0.0013 | 2.7 | 1.4 | AFUN011500 | 2,297.9 | 686.9 | Sulfite oxidase |
| AFUN000619 | 0.0025 | 2.4 | 1.3 | GRX2 | 768.9 | 303.6 | Glutaredoxin |
| AFUN011515 | 0.0063 | 2.0 | 1.0 | TPX4 | 3,567.4 | 1,179.5 | Thioredoxin peroxidase 4 |
| AFUN019604 | 0.0042 | 2.7 | 1.4 | AFUN019604 | 30.6 | 10.7 | Glutaredoxin-3 |
| AFUN001952 | 0.0049 | 4.0 | 2.0 | AFUN001952 | 1,159.8 | 267.4 | Uncoupling protein 2, mitochondrial |
| Proteases and others | |||||||
| AFUN016100 | 0.0059 | 2.1 | 1.1 | AFUN016100 | 2,012.7 | 648.1 | Alpha-amylase |
| AFUN019614 | 0.0039 | 3.0 | 1.6 | AFUN019614 | 1,413.7 | 323.6 | Ankyrin repeat |
| AFUN004002 | 0.0021 | 2.7 | 1.4 | AFUN004002 | 17,374.3 | 4,616.8 | Argininosuccinate lyase |
| AFUN019821 | 0.0126 | 2.0 | 1.0 | AFUN019821 | 905.3 | 334.1 | Carboxypeptidase A |
| AFUN021240 | 0.0013 | 17.8 | 4.2 | AFUN021240 | 1,050.2 | 46.2 | Carboxypeptidase Q |
| AFUN021239 | 0.0079 | 11.5 | 3.5 | AFUN021239 | 807.5 | 75.4 | Carboxypeptidase Q |
| AFUN022011 | 0.0200 | 3.2 | 1.7 | AFUN022011 | 50,117.5 | 15,637.6 | Chymotrypsin |
| AFUN007012 | 0.0442 | 5.0 | 2.3 | AFUN007012 | 12.3 | 4.8 | Chymotrypsin-like protease |
| AFUN016591 | 0.0043 | 7.1 | 2.8 | AFUN016591 | 24,258.5 | 2,746.8 | Trypsin |
| AFUN016449 | 0.0222 | 2.3 | 1.2 | AFUN016449 | 3,458.1 | 1,127.3 | Trypsin |
| AFUN020614 | 0.0052 | 3.7 | 1.9 | AFUN020614 | 3,655.9 | 848.5 | Trypsin-6 |
| AFUN022010 | 0.0131 | 4.3 | 2.1 | AFUN022010 | 101,129.8 | 20,343.8 | Serine protease; Trypsin-1 |
| AFUN020946 | 0.0192 | 23.3 | 4.5 | AFUN020946 | 153.9 | 10.8 | Serine-type endopeptidase -Chymotrypsin-2 |
| Cuticular proteins | |||||||
| AFUN011620 | 0.0154 | 7.8 | 3.0 | AFUN011620 | 92.4 | 11.7 | Cuticle protein |
| AFUN009937 | 0.0101 | 3.9 | 2.0 | AFUN009937 | 5.0 | 1.4 | Cuticular protein RR-1 family |
| AFUN006418 | 0.0235 | 2.8 | 1.5 | AFUN006418 | 282.1 | 72.0 | Cuticular protein RR-2 family |
| AFUN020923 | 0.0259 | 15.7 | 4.0 | AFUN020923 | 57.6 | 3.1 | Cuticular protein RR-2 family |
| AFUN021592 | 0.0155 | 2.4 | 1.3 | AFUN021592 | 194.0 | 54.1 | Larval cuticle protein LCP-30 |
| Gustatory/odorant receptors | |||||||
| AFUN015936 | 0.0107 | 5.5 | 2.5 | Gr20 | 731.4 | 124.2 | Gustatory receptor |
| AFUN015933 | 0.0092 | 2.7 | 1.4 | Gr45 | 24.4 | 7.7 | Gustatory receptor |
| AFUN008090 | 0.0089 | 2.7 | 1.4 | Or36 | 19.9 | 8.1 | Odorant receptor |
| AFUN008522 | 0.0276 | 2.2 | 1.2 | Or39 | 63.3 | 22.0 | Odorant receptor |
| AFUN018655 | 0.0028 | 8.2 | 3.0 | AFUN018655 | 13.0 | 0.4 | Odorant receptor |
| MicroRNA | |||||||
| AFUN017296 | 0.0002 | 4.3 | 2.1 | mir-279 | 4.9 | 0.8 | MicroRNA mir-279 |
| AFUN017073 | 0.0403 | 2.9 | 1.5 | mir-33 | 4.5 | 1.1 | MicroRNA mir-33 |
| Transposon | |||||||
| AFUN019794 | 0.0003 | 83.2 | 6.4 | AFUN019794 | 67,882.0 | 520.4 | BEL12_AG transposon polyprotein |
| AFUN019813 | 0.0053 | 22.9 | 4.5 | AFUN019813 | 4,612.4 | 121.4 | Retrovirus-related Pol polyprotein from transposon TNT 1-94 |
| Transcription factors | |||||||
| AFUN002438 | 0.0039 | 4.2 | 2.1 | AFUN002438 | 446.7 | 102.3 | Transcription elongation factor 1 homolog |
| AFUN019110 | 0.0018 | 2.9 | 1.5 | AFUN019110 | 631.4 | 183.8 | Transcription factor Adf-1 |
| AFUN021815 | 0.0042 | 2.2 | 1.1 | AFUN021815 | 422.6 | 152.5 | Transcription factor grauzone |
| AFUN021263 | 0.0038 | 3.6 | 1.9 | AFUN021263 | 425.8 | 93.9 | Transcription initiation factor TFIID subunit |
| AFUN011301 | 0.0040 | 2.6 | 1.4 | AFUN011301 | 1,434.7 | 388.1 | Transcription initiation factor TFIID subunit 12 |
| AFUN011301 | 0.0040 | 2.6 | 1.4 | AFUN011301 | 1,434.7 | 388.1 | Transcription initiation factor TFIID subunit 12 |
| AFUN021364 | 0.0370 | 2.1 | 1.1 | AFUN021364 | 408.3 | 155.2 | Transcription initiation factor TFIIH subunit |
Description, gene annotation; FC, fold-change; FUMOZ/FANG reads, total read pairs across replicates; Log FC, log2 fold-change; P, FDR-adjusted P-value.