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. 2021 Dec 4;12(1):jkab385. doi: 10.1093/g3journal/jkab385

Table 4.

Waist–hip ratio association of rs78058190 in UK biobank

Covariates SNPTEST P SNPTEST β ANGSD P ANGSD β
Age, sex, BMI, and PC 1–10 8.02 × 10–12 0.030 7.62 × 10−12 0.030
Age, sex, BMI, and PC 1–10 0.00086 0.015 1.04 × 10−6 0.031427
rs113414093 (R2 0.58)
Age, sex, BMI, and PC 1–10 7.39 × 10−6 0.020 1.3 × 10−6 0.024
rs116204487 (R2 0.20)
Age, sex, BMI, and PC 1–10 1.21 × 10−5 0.019 7.14 × 10−7 0.024
rs148358468 (R2 0.19)

This table shows the P-value and estimated effect size (β), for the association of rs78058190 with waist–hip ratio (inverse quantile transformed to a standard normal distribution) when conditioning on genetic variants in linkage disequilibrium LD with rs78058190. The R2 values are shown in the table and are based on the LDproxy tool that is part of LDlink (Machiela and Chanock 2015). Results for rs113414093, rs116204487, and rs148358468 conditional on rs78058190 can be found in Supplementary Table S1 and S2.