TABLE 2.
Long-term effects of a single high dose of STZ on blood glucose and pancreatic insulin levels in APNG−/− mice
| Treatment | Blood glucose level (mM)a (no. of mice) | Pancreatic insulin level (ng/mg)a (no. of mice) |
|---|---|---|
| None (controls) | 5.48 ± 0.89 (7) | 82.3 ± 28 (6) |
| STZ (140 mg/kg) | 13.1 ± 3.3 (11)b | 7.97 ± 5.19 (7) |
a
P < 0.001 for comparisons between controls and STZ-treated mice. Values are expressed as the mean ± standard devation.
b
Values do not include one animal, where the glucose level was >44 mM.