Skip to main content
. 2021 Oct 13;50(D1):D654–D664. doi: 10.1093/nar/gkab920

Table 1.

Distribution of chains across human protein kinase families and conformational state labels.

Spatial label Dihedral label Annotation AGC CAMK CK1 CMGC NEK RGC STE TKL TYR Other Total
DFGin BLAminus Active 306 823 189 1187 0 0 216 401 545 172 3839
BLBplus SRC-inactive 3 9 0 133 0 0 82 46 358 18 649
ABAminus Active-like 60 45 3 95 0 0 11 9 310 88 621
BLBminus 0 7 0 121 1 0 19 18 54 10 230
BLAplus FGFR-inactive 3 2 0 3 0 0 4 40 152 1 205
BLBtrans CDK-inactive 0 0 0 124 0 0 7 1 62 3 197
None 14 40 2 76 14 0 26 21 200 24 417
DFGinter BABtrans 0 1 0 0 4 0 2 0 13 0 20
None AURKA-inactive 10 69 0 15 2 0 7 4 32 0 139
DFGout BBAminus Type-2 binding 7 6 2 58 0 0 15 96 233 5 422
None DFGout-like 11 10 0 32 9 0 42 14 101 7 226
None None 7 43 0 87 19 0 17 2 32 5 212
Total - 421 1055 196 1931 49 0 448 652 2092 333 7177