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. 2021 Nov 10;50(D1):D640–D647. doi: 10.1093/nar/gkab1034

Figure 2.

Figure 2.

Results of querying IID with 116 psoriatic arthritis genes from DisGeNET (67). This query included three types of annotations: mutation effects, conservation across species, and druggability. (A) Visualization of a subset of retrieved PPIs comprising high degree query proteins (violet) and interaction partners (blue). (B) Mutations with known effects on retrieved PPIs. (C) Conservation of retrieved PPIs across species. (D) Drugs targeting one or both proteins of retrieved PPIs.