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. 2021 Oct 28;50(D1):D1398–D1407. doi: 10.1093/nar/gkab953

Figure 1.

Figure 1.

A typical page in TTD providing prodrug information. The structures of both prodrug and its parent drug are provided along with the bioconversion enzyme or condition. Structural variation between prodrug and parent drug is highlighted in orange. The strategy for prodrug design, and the enhancement in the pharmaceutical property from parent drug to its prodrug are also described.