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. 2021 Sep 27;50(D1):D1408–D1416. doi: 10.1093/nar/gkab853

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Result page and distinctive web components of VannoPortal. (A) Conservation scores and positive selection scores in the ‘Evolution’ panel. (B) A composite viewer showing LD structure, disease/trait association tracks and evidence table in the ‘Phenotype’ panel. (C) Tissue/cell type-specific regulatory variant prioritization function in the ‘Regulatory potential’ panel. (D) Two rich tables displaying critical histone marks, chromatin states, and TF binding sites across hundreds of tissue/cell type-specific samples at variant locus, from Roadmap Epigenomics or EpiMap projects. (E) A circular plot showing significant 5 kb Hi-C chromatin interactions between variant locus and its target region. (F) Real-time motif scanning table for the predicted allele-specific effect of TF binding. (G) Genome-scale pathogenic scores in the ‘Pathogenicity’ panel.