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. 2022 Jan 4;12(1):e054741. doi: 10.1136/bmjopen-2021-054741

Figure 5.

Figure 5

Top 30 factors associated with PHQ-9 score adjusted by age, sex, age by sex interaction, race, ethnicity, socioeconomic status, health behaviours, medical conditions, symptoms, allergies and physical function. LASSO regression model 5 comprised age, sex, age by sex interaction, race, ethnicity, socioeconomic status, health behaviours, medical conditions (except mental health disorder diagnoses or disorders directly related to mental health or depression), symptoms (except those that are directly related to mental health or depression), allergies, and physical function. The LASSO-predicted value was used to estimate a covariate-adjusted effect for all other candidate variables. ALT, alanine aminotransferase; AST, aspartate aminotransferase; GFR, glomerular filtration rate; HbA1c, haemoglobin A1c; HDL, high density lipoprotein; LASSO, least absolute shrinkage and selection operator; LDL, low density lipoprotein; MCH, mean corpuscular haemoglobin; MCHC, mean corpuscular haemoglobin concentration; MCV, mean corpuscular volume; MDRD, modification of diet in renal disease; MPV, mean platelet volume; pH, potential hydrogen; PHQ-9, Patient Health Questionnaire-9; RBC, red blood cell; TSH, thyroid-stimulating hormone; WBC, white blood cell.