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. 2022 Jan 4;12(1):e049325. doi: 10.1136/bmjopen-2021-049325

Table 1.

Baseline characteristics of the population by tertile of ALBI, median (IQR), or N (%), or means±SD

Variable Overall
(n=9749)
Tertile 1 ALBI ≤2.59 (n=3250) Tertile 2 ALBI −2.59 to −2.27 (n=3250) Tertile 3 ALBI ≥2.27 (n=3249) P value
Age (years) 69.1±13.6 67.9±12.8 70.2±13.1 69.4±14.6 <0.001
Male (n (%)) 5158 (52.9) 1650 (50.8) 1731 (53.3) 1777 (54.7) 0.006
NYHA grading (n (%)) <0.001
 Ⅱ 1954 (20.0) 988 (30.4) 637 (19.6) 329 (10.1)
 Ⅲ 4207 (43.2) 1434 (44.1) 1428 (43.9) 1345 (41.4)
 Ⅳ 3588 (36.8) 828 (25.5) 1185 (36.5) 1575 (48.5)
Heart rate on admission, bpm 87.7±22.3 85.0±21.0 87.6±22.4 90.5±23.2 <0.001
SBP on admission, mm Hg 135.2±22.7 136.1±21.0 135.9±22.7 133.5±24.1 <0.001
SGPT, U/L 25.5±11.9 25.5±11.0 25.2±11.9 26.0±12.7 0.046
SGOT, U/L 31 (26,35) 34 (23,34) 31 (24,35) 33 (28,37) <0.001
Albumin, g/L 37.1±4.5 41.3±2.5 37.4±2.0 32.6±3.5 <0.001
TBIL, umol/L 16.2±12.1 12.7±6.8 15.2±8.7 20.6±16.9 <0.001
LDL, mmol/L 2.52±0.91 2.70±0.94 2.52±0.85 2.36±0.92 <0.001
Creatinine, mg/dL 1.07±0.51 1.01±0.45 1.06±0.50 1.16±0.56 <0.001
Haemoglobin, g/L 127.6±21.9 132.0±19.6 128.1±21.0 122.8±24.1 <0.001
Serum Na, mmol/L 138.9±3.9 139.5±3.3 139.2±3.6 137.9±4.5 <0.001
FBG, mmol/L 6.5±1.6 6.6±1.7 6.5±1.4 6.4±1.6 <0.001
cTNI, ng/mL 0.04 (0.01, 0.28) 0.03 (0.01, 0.15) 0.04 (0.01, 0.31) 0.06 (0.02, 0.35) <0.001
NT-pro-BNP, pg/mL 2538 (986, 5850) 1376 (570, 3284) 2492 (1066, 5419) 5186 (1987, 9085) <0.001
LVEF, % 48.7±11.3 50.4±11.0 48.9±11.3 46.9±11.3 <0.001
comorbidities, n (%)
 CHD 6282 (64.4) 2184 (67.2) 2129 (65.5) 1969 (60.6) <0.001
 Hypertension 5948 (61.0) 2149 (63.8) 2129 (63.4) 1860 (55.8) <0.001
 AF 3086 (31.7) 1091 (33.6) 1094 (33.7) 901 (27.7) <0.001
 DM 3118 (32.0) 1070 (32.9) 1023 (31.5) 1025 (31.5) 0.371
Smoking(n (%)) 2664 (27.3) 919 (28.3) 855 (26.3) 890 (27.4) 0.203
In-hospital mortality 343 (3.5) 67 (2.1) 78 (2.4) 198 (6.1) <0.001

AF, atrial fibrillation; ALBI, albumin-bilirubin; CHD, coronary heart disease; cTNI, cardiac troponin I; DM, diabetes mellitus; FBG, fasting blood glucose; LDL, Low Density Lipoprotein; LVEF, left ventricular ejection fraction; NT-proBNP, n‐terminal brain natriuretic peptide; NYHA, New York Heart Association; SBP, systolic blood pressure; Serum Na, serum sodium; SGOT, serum glutamic oxaloacetic transaminase; SGPT, serum glutamate-pyruvate transaminase; TBIL, total bilirubin.