Figure 1.

Anti-EFG1 2′OMe oligomer toxicity evaluation in a G. mellonella model

(A) Survival curves of larvae injected with 40 and 100 nM of anti-EFG1 2′OMe oligomer. For each condition, 10 larvae were injected with 40 and 100 nM of oligomer and their survival was monitored over 96 h. (B) Relative LDH activity released and total number of hemocytes counted after 4 and 24 h after injection with 100 nM of anti-EFG1 2′OMe oligomer. As controls, larvae were injected only with PBS.