Table 2:
Significant taxa at between HLA-DQ8, HLA-DR3, and HLA-DR3.DQ8 at the phylum through genus ranks
| Taxa | Mean (Standard Error) Relative Abundance | P-value | Q-value | ||
|---|---|---|---|---|---|
| HLA-DQ8 | HLA-DR3 | HLA-DR3.DQ8 | |||
| Phylum | |||||
| Campilobacterota | 8.04E-2 (1.28E-2) | 4.47E-2 (1.04E-2) | 1.26E-1 (1.87E-2) | 9.95E-04 | 1.99E-03 |
| Deferribacterota | 1.93E-2 (6.35E-3) | 5.65E-3 (2.32E-3) | 3.00E-2 (6.99E-3) | 4.32E-04 | 1.15E-03 |
| Desulfobacterota | 1.31E-3 (4.10E-4) | 9.15E-3 (2.39E-3) | 4.35E-3 (1.21E-3) | 3.91E-04 | 1.15E-03 |
| Patescibacteria | 1.57E-2 (2.54E-3) | 3.08E-2 (3.41E-3) | 6.35E-3 (8.80E-4) | 1.29E-06 | 1.03E-05 |
| Proteobacteria | 1.45E-2 (5.56E-3) | 2.46E-2 (4.57E-3) | 3.24E-2 (3.20E-3) | 5.95E-03 | 9.52E-03 |
| Class | |||||
| Campylobacteria | 8.04E-2 (1.28E-2) | 4.47E-2 (1.04E-2) | 1.26E-1 (1.87E-2) | 9.95E-04 | 1.99E-03 |
| Coriobacteriia | 2.22E-3 (3.69E-4) | 7.01E-3 (1.18E-3) | 2.25E-3 (3.47E-4) | 3.67E-04 | 1.08E-03 |
| Deferribacteres | 1.93E-2 (6.35E-3) | 5.65E-3 (2.32E-3) | 3.00E-2 (6.99E-3) | 4.32E-04 | 1.08E-03 |
| Desulfovibrionia | 1.31E-3 (4.10E-4) | 9.15E-3 (2.39E-3) | 4.35E-3 (1.21E-3) | 3.91E-04 | 1.08E-03 |
| Gammaproteobacteria | 1.45E-2 (5.56E-3) | 2.46E-2 (4.57E-3) | 3.24E-2 (3.20E-3) | 5.95E-03 | 9.92E-03 |
| Saccharimonadia | 1.57E-2 (2.54E-3) | 3.08E-2 (3.41E-3) | 6.35E-3 (8.80E-4) | 1.29E-06 | 1.29E-05 |
| Order | |||||
| Acholeplasmatales | 2.55E-2 (5.69E-3) | 8.12E-3 (2.21E-3) | 1.14E-2 (1.46E-3) | 5.24E-03 | 1.11E-02 |
| Burkholderiales | 1.45E-2 (5.56E-3) | 2.46E-2 (4.57E-3) | 3.24E-2 (3.20E-3) | 5.95E-03 | 1.12E-02 |
| Campylobacterales | 8.04E-2 (1.28E-2) | 4.47E-2 (1.04E-2) | 1.26E-1 (1.87E-2) | 9.95E-04 | 2.42E-03 |
| Clostridiales | 4.99E-3 (1.94E-3) | 2.50E-3 (8.39E-4) | 1.81E-2 (3.53E-3) | 5.47E-05 | 3.10E-04 |
| Coriobacteriales | 2.22E-3 (3.69E-4) | 7.01E-3 (1.18E-3) | 2.25E-3 (3.47E-4) | 3.67E-04 | 1.22E-03 |
| Deferribacterales | 1.93E-2 (6.35E-3) | 5.65E-3 (2.32E-3) | 3.00E-2 (6.99E-3) | 4.32E-04 | 1.22E-03 |
| Desulfovibrionales | 1.31E-3 (4.10E-4) | 9.15E-3 (2.39E-3) | 4.35E-3 (1.21E-3) | 3.91E-04 | 1.22E-03 |
| Peptococcales | 3.19E-4 (6.51E-5) | 1.13E-4 (4.46E-5) | 2.95E-4 (8.24E-5) | 8.71E-03 | 1.48E-02 |
| Peptostreptococcales_Tissierellales | 3.40E-3 (1.22E-3) | 7.74E-4 (1.68E-4) | 1.02E-2 (2.45E-3) | 3.47E-06 | 2.95E-05 |
| Saccharimonadales | 1.57E-2 (2.54E-3) | 3.08E-2 (3.41E-3) | 6.35E-3 (8.80E-4) | 1.29E-06 | 2.19E-05 |
| Family | |||||
| Acholeplasmataceae | 2.55E-2 (5.69E-3) | 8.12E-3 (2.21E-3) | 1.14E-2 (1.46E-3) | 5.24E-03 | 1.28E-02 |
| Bacteroidaceae | 1.47E-1 (3.04E-2) | 1.83E-1 (1.65E-2) | 1.14E-1 (9.09E-3) | 1.85E-02 | 3.24E-02 |
| Butyricicoccaceae | 2.33E-3 (6.39E-4) | 1.37E-3 (3.02E-4) | 3.24E-3 (4.03E-4) | 5.97E-03 | 1.28E-02 |
| Clostridiaceae | 4.99E-3 (1.94E-3) | 2.50E-3 (8.39E-4) | 1.81E-2 (3.53E-3) | 5.47E-05 | 5.10E-04 |
| Deferribacteraceae | 1.93E-2 (6.35E-3) | 5.65E-3 (2.32E-3) | 3.00E-2 (6.99E-3) | 4.32E-04 | 2.01E-03 |
| Desulfovibrionaceae | 1.31E-3 (4.10E-4) | 9.15E-3 (2.39E-3) | 4.35E-3 (1.21E-3) | 3.91E-04 | 2.01E-03 |
| Eggerthellaceae | 2.22E-3 (3.69E-4) | 7.01E-3 (1.18E-3) | 2.25E-3 (3.47E-4) | 3.67E-04 | 2.01E-03 |
| Helicobacteraceae | 8.04E-2 (1.28E-2) | 4.47E-2 (1.04E-2) | 1.26E-1 (1.87E-2) | 9.95E-04 | 3.48E-03 |
| Marinifilaceae | 2.89E-2 (5.44E-3) | 1.13E-2 (1.66E-3) | 2.73E-2 (4.44E-3) | 8.73E-04 | 3.48E-03 |
| Peptococcaceae | 3.19E-4 (6.51E-5) | 1.13E-4 (4.46E-5) | 2.95E-4 (8.24E-5) | 8.71E-03 | 1.63E-02 |
| Peptostreptococcaceae | 3.20E-3 (1.21E-3) | 3.28E-4 (1.46E-4) | 1.00E-2 (2.44E-3) | 6.94E-07 | 1.80E-05 |
| Prevotellaceae | 1.38E-1 (2.75E-2) | 6.32E-2 (8.57E-3) | 1.12E-1 (9.97E-3) | 2.58E-03 | 8.02E-03 |
| Saccharimonadaceae | 1.57E-2 (2.54E-3) | 3.08E-2 (3.41E-3) | 6.35E-3 (8.80E-4) | 1.29E-06 | 1.80E-05 |
| Streptococcaceae | 1.25E-3 (4.37E-4) | 4.93E-4 (9.65E-5) | 1.72E-4 (5.96E-5) | 6.39E-03 | 1.28E-02 |
| Sutterellaceae | 1.45E-2 (5.56E-3) | 2.46E-2 (4.57E-3) | 3.24E-2 (3.20E-3) | 5.95E-03 | 1.28E-02 |
| Tannerellaceae | 5.37E-2 (7.87E-3) | 7.14E-2 (9.97E-3) | 3.24E-2 (7.21E-3) | 4.83E-03 | 1.28E-02 |
| Genus | |||||
| Rikenellaceae;Alistipes | 6.39E-2 (7.60E-3) | 2.91E-2 (4.90E-3) | 2.96E-2 (3.61E-3) | 1.04E-03 | 3.29E-03 |
| Prevotellaceae;Alloprevotella | 1.37E-1 (2.76E-2) | 4.88E-2 (7.02E-3) | 1.01E-1 (1.01E-2) | 2.88E-04 | 1.83E-03 |
| Anaeroplasmataceae;Anaeroplasma | 2.55E-2 (5.69E-3) | 8.12E-3 (2.21E-3) | 1.14E-2 (1.46E-3) | 5.24E-03 | 1.30E-02 |
| Bacteroidetes;Bacteroides | 1.47E-1 (3.04E-2) | 1.83E-1 (1.65E-2) | 1.14E-1 (9.09E-3) | 1.85E-02 | 3.77E-02 |
| Clostridiaceae;Butyricicoccus | 1.63E-3 (6.27E-4) | 2.05E-4 (8.03E-5) | 1.21E-3 (2.59E-4) | 6.34E-05 | 5.17E-04 |
| Candidatus Saccharimonas | 1.57E-2 (2.54E-3) | 3.08E-2 (3.41E-3) | 6.35E-3 (8.80E-4) | 1.29E-06 | 3.67E-05 |
| Clostridiaceae;Clostridium sensu stricto 1 | 3.96E-3 (1.96E-3) | 3.87E-4 (3.21E-4) | 1.33E-2 (3.48E-3) | 1.05E-05 | 1.50E-04 |
| Proteobacteria;Desulfovibrio | 1.02E-3 (3.64E-4) | 8.82E-3 (2.41E-3) | 4.20E-3 (1.23E-3) | 3.22E-04 | 1.84E-03 |
| Eggerthellaceae;Enterorhabdus | 1.44E-3 (2.58E-4) | 3.71E-3 (7.55E-4) | 1.57E-3 (2.20E-4) | 3.79E-03 | 1.03E-02 |
| Helicobacteraceae;Helicobacter | 7.90E-2 (1.25E-2) | 4.33E-2 (1.02E-2) | 1.24E-1 (1.84E-2) | 1.04E-03 | 3.29E-03 |
| Eubacteriales;Intestinimonas | 8.09E-4 (1.34E-4) | 2.27E-3 (3.48E-4) | 8.77E-4 (9.55E-5) | 1.80E-03 | 5.39E-03 |
| Lachnospiraceae;Marvinbryantia | 2.69E-3 (8.47E-4) | 6.32E-3 (1.55E-3) | 6.30E-4 (2.91E-4) | 1.75E-05 | 2.00E-04 |
| Deferribacteraceae;Mucispirillum | 1.93E-2 (6.35E-3) | 5.65E-3 (2.32E-3) | 3.00E-2 (6.99E-3) | 4.32E-04 | 2.06E-03 |
| Porphyromonadaceae;Odoribacter | 2.89E-2 (5.44E-3) | 1.13E-2 (1.66E-3) | 2.73E-2 (4.44E-3) | 8.73E-04 | 3.11E-03 |
| Oscillospiraceae;Paludicola | 1.04E-4 (2.56E-5) | 1.21E-4 (5.75E-5) | 3.00E-4 (7.30E-5) | 1.40E-02 | 2.96E-02 |
| Bacteroidetes;Parabacteroides | 5.37E-2 (7.87E-3) | 7.14E-2 (9.97E-3) | 3.24E-2 (7.21E-3) | 4.83E-03 | 1.25E-02 |
| Sutterellaceae;Parasutterella | 1.45E-2 (5.56E-3) | 2.46E-2 (4.57E-3) | 3.24E-2 (3.20E-3) | 5.95E-03 | 1.41E-02 |
| Peptococcaceae;Peptococcus | 3.19E-4 (6.51E-5) | 1.13E-4 (4.46E-5) | 2.95E-4 (8.24E-5) | 8.71E-03 | 1.91E-02 |
| Prevotellaceae UCG 1 | 1.14E-3 (9.72E-4) | 1.44E-2 (3.02E-3) | 1.11E-2 (2.07E-3) | 4.46E-04 | 2.06E-03 |
| Bacteroidetes;Rikenella | 6.41E-3 (9.18E-4) | 1.50E-2 (1.97E-3) | 1.45E-2 (1.21E-3) | 1.18E-04 | 8.39E-04 |
| Peptostreptococcaceae;Romboutsia | 3.20E-3 (1.21E-3) | 3.28E-4 (1.46E-4) | 1.00E-2 (2.44E-3) | 6.94E-07 | 3.67E-05 |
| Lachnospiraceae;Roseburia | 2.55E-3 (5.37E-4) | 4.21E-3 (1.60E-3) | 9.73E-3 (1.56E-3) | 4.69E-04 | 2.06E-03 |
| Streptococcaceae;Streptococcus | 1.25E-3 (4.37E-4) | 4.93E-4 (9.65E-5) | 1.72E-4 (5.96E-5) | 6.39E-03 | 1.46E-02 |
| Erysipelotrichaceae;Turicibacter | 1.73E-2 (6.46E-3) | 2.00E-4 (2.00E-4) | 9.91E-3 (2.25E-3) | 2.13E-06 | 4.05E-05 |
Kruskall-Wallis test with Benjamini-Hochberg adjustment was performed on sample-scaled counts at a significance level of 0.05 to identify differentially abundant taxa. Q-values are the adjusted P-values.