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G-quadruplex structures in aptamers and their stabilization.A, a schematic structure of a G-quadruplex, which can be stabilized by a metal ion, e.g., K+, or flat molecules, for example those shown in panel B. B, structures of L1H1-7OTD and TmPyP4, which have been used as stabilizers of a G-quadruplex in the anti-αSyn aptamer T-SO530.
