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Developmental origin of the gut phenotype in MTG8 exon 2-targeted mice. Hematoxylin and eosin-stained transverse sections through the region of the umbilical hernia of MTG8 exon 2-targeted (−/−) and control (+/+) E17.5 embryos are shown. In the former, the double-headed arrow indicates the communication between the abdominal cavity and the umbilical hernia, which is still prominent, whereas it has normally disappeared at this stage in control littermates.
