Table 1. The 2 arms of the intra-operative drug treatment.
Arm | Participants will be randomised to one of the following 2 arms: | |||
---|---|---|---|---|
Agent | Dose | Temperature | Route | |
NIPEC | Cisplatin | 100 mg/m2 | 37 (36.5–37.5)°C | IP |
Q90mins | ||||
HIPEC | Cisplatin | 100 mg/m2 | 42 (41.5–42.5)°C | IP |
Q90mins |
HIPEC, hyperthermic intraperitoneal chemotherapy; IP, intraperitoneal; NIPEC, normothermic intraperitoneal chemotherapy.