TABLE 2.
Defined daily doses and blood pressures of 287 patients at visits 1–3
| Variable | Visit 1 baseline | Visit 2 1 month later | Visit 3 1 year later | P |
| Defined daily doses (units) | 1.63 (1.12) | 1.62 (1.12) | 1.68 (1.17) | 0.12 |
| Attended office measurement | ||||
| SBP (mmHg) | 139.2 (16.9) | 138.0 (15.5) | 138.3 (17.1) | 0.39 |
| DBP (mmHg) | 74.6 (12.0) | 74.1 (12.1) | 75.0 (12.7) | 0.20 |
| Pulse rate (beats per minute) | 76.9 (12.7) | 76.0 (12.4) | 76.4 (11.6) | 0.23 |
| Unattended office measurement | ||||
| SBP (mmHg) | 128.9 (15.9) | 127.4 (14.8) | 127.8 (14.4) | 0.17 |
| DBP (mmHg) | 70.5 (11.6) | 70.0 (11.7) | 69.8 (11.2) | 0.30 |
| Pulse rate (beats per minute) | 72.8 (11.8) | 72.2 (12.1) | 72.1 (11.3) | 0.32 |
| Combined home measurement | ||||
| SBP (mmHg) | 125.7 (8.4) | 124.9 (9.1) | 125.8 (8.4)∗ | 0.083 |
| DBP (mmHg) | 72.9 (8.6) | 72.4 (8.8) | 72.6 (8.2) | 0.22 |
| Pulse rate (beats per minute) | 67.7 (8.5) | 67.4 (8.3) | 67.8 (8.3) | 0.33 |
| Morning home measurement | ||||
| SBP (mmHg) | 127.9 (9.3) | 127.0 (9.8)∗ | 127.8 (9.1) | 0.094 |
| DBP (mmHg) | 75.1 (8.9) | 74.4 (9.2)∗ | 74.4 (8.6) | 0.064 |
| Pulse rate (beats per minute) | 66.3 (9.0) | 66.1 (8.7) | 66.5 (8.7) | 0.42 |
| Evening home measurement | ||||
| SBP (mmHg) | 123.4 (9.9) | 122.8 (10.5) | 123.7 (9.8) | 0.16 |
| DBP (mmHg) | 70.6 (9.3) | 70.2 (9.4) | 70.7 (8.8) | 0.29 |
| Pulse rate (beats per minute) | 69.1 (9.2) | 68.8 (9.0) | 69.2 (9.1) | 0.34 |
Values are shown as means (SD). Evening home measurements were unavailable in seven patients at visit 1 [one from Katsuya Clinic (KC) and six from Yokohama Sotetsu bldg. Clinic (YSBC)], eight patients at visits 2 (two from KC and six from YSBC), and 11 patients at visit 3 (one from KC and 10 from YSBC). P values were calculated by a repeated-measures mixed linear model to take missing values into account and represent the differences among the visits. BP, blood pressure. Significance of differences from the left adjacent visit: ∗P < 0.05.