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. 2021 Dec 8:NEJMoa2115624. doi: 10.1056/NEJMoa2115624

Table 2. Association of Confounding Variables with Death Due to Covid-19.*.

Variable Hazard Ratio for Death Due to Covid-19 (95% CI) P Value
Booster received 0.10 (0.07–0.14) <0.001
Age 1.10 (1.09–1.12) <0.001
Male sex 2.49 (1.82–3.41) <0.001
Socioeconomic status 0.98 (0.92–1.04) 0.45
Diabetes 1.29 (0.96–1.72) 0.09
Chronic obstructive pulmonary disease 1.31 (0.86–1.99) 0.22
Chronic kidney failure 2.27 (1.63–3.15) <0.001
Ischemic heart disease 0.96 (0.69–1.32) 0.79
Chronic heart failure 1.41 (0.95–2.09) 0.09
Obesity 1.17 (0.87–1.58) 0.30
Lung cancer 3.20 (1.49–6.87) 0.003
History of cerebrovascular accident 1.54 (1.08–2.17) 0.02
History of transient ischemic attack 0.87 (0.50–1.51) 0.63
History of smoking 1.10 (0.82–1.49) 0.52
*

Age was a continuous variable, and socioeconomic status was an ordinal variable; all other variables were dichotomous (present vs. absent). Covid-19 denotes coronavirus disease 2019.