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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Adv Drug Deliv Rev. 2021 Nov 18;180:114057. doi: 10.1016/j.addr.2021.114057

Table 1.

Summary of antimicrobial blue light killing of microbes as determined by numerous studies published 2017 -present

Microbes Wavelength (nm) Radiant exposure (J/cm2) Viability loss Reference
S. pyogenes 405 nm 36 - 50 J/cm2 99.99 - 99.999999% [37,81]
N. gonorrhoeae 405 nm 45 – 108 J/cm2 99.99999% [49,50]
E. coli 405 - 420 nm 59 - 603 J/cm2 90 - 99.999% [23,27,29,33,34,60,75]
445 nm 540 J/cm2 <90% [34]
S. aureus 400 - 420 nm 50 - 841 J/cm2 71 - >99.999% [17,23,27,37,38,54,68,76,80,81]
450 nm (pulsed) 4.5 - 7.6 J/cm2 80 - 100% [47]
470 nm 603.44 J/cm2 80% [65]
S. carnosus 405 - 440 nm 70 – 270 J/cm2 90 - 99.9% [52,62]
450 – 470 nm 210 -500 J/cm2 99 - 99.9% [53,62]
S. epidermidis 405 nm 50 – 122 J/cm2 99- 99.999% [37,81]
S. agalactiae 450 nm (pulsed 22.8 J/cm2 5.5 - 11% [105]
P. aeruginosa 405 - 415 nm 10 – 463 J/cm2 >90 - 100% [17,23,27,69,75,81,89]
470 nm 603.44 J/cm2 65% [20]
P. gingivalis 405 nm 60 J/cm2 64.5% [2]
S. typhimurium 413 nm 463.38 J/cm2 99.9% [27]
S. enteritidis 405 nm 729 J/cm2 >99.9999 [28]
A. actinomycetemcomitans 405 nm 60 J/cm2 49.7% [40]
M. fortuitum 405 – 413 nm 240 – 583.5 J/cm2 93 - 99.999% [17,27]
C. jejuni 405 nm 24 J/cm2 81.82% [51]
463 nm 24 J/cm2 99.81% [51]
P. fluorescens 400 - 420 nm 99 - 420 J/cm2 >99 – 100% [18,19,62]
450 - 470 nm 500 - 604.8 J/cm2 90 - 99.9% [62] [63] [19]
M. catarrhalis 405 nm 216 J/cm2 99.99% [46,47]
P. acnes 450 nm (pulsed) 20 – 45 J/cm2 100% [46,47]
C. sakazakii 415 nm 240 J/cm2 99.999999% [67]
S. cerevisiae 405 nm 182 J/cm2 90% [22]
450 nm 526 J/cm2 90% [22]
T. cruzi 405 nm 270 J/cm2 >99% [39]
C. albicans 405 - 415 nm 50 – 108 J/cm2 >80 - 99.9999% [72,81,90]
450 nm 360 J/cm2 >80% [72]
C. vaginitis 405 – 415 nm 225 J/cm2 >99.9% [79]
470 nm 360 J/cm2 23.44% [79]
Prototheca Spp. 410 nm 137 – 320 J/cm2 99 -99.0% [25]
K. pneumoniae 410 nm 108 – 1903 J/cm2 66.1 - 100% [26,81,87]
E. moraviensis 405 nm 200 J/cm2 90% [58]
450 nm 750 J/cm2 90% [58]
E. faecium 405 nm 540 J/cm2 99.99% [81]
L. monocytogenes 460 – 470 nm 604.8 J/cm2 >99.999% [63]
A. baumannii 405 nm 144 - 270 J/cm2 99.99 - 99.9999 [75,81,86]
A. flavus 405 nm 540 J/cm2 <90% [91]
A. fumigatus 405 nm 540 J/cm2 <90% [91]
F. oxysporum 405 nm 540 J/cm2 <90% [91]
B. cereus 405 nm 50 J/cm2 99.9% [37]
S. mutans 405 nm 340 – 831 J/cm2 48 - 54% [42]
L. rubrilucens 450 – 470 nm 300 – 500 J/cm2 >99.999% [21]
Enterococcus Spp. 405 nm 360 J/cm2 99.999% [81]
SARS-CoV-2 450 - 470 nm 144 J/cm2 >99% [56]
Phi6 405 nm 1400 J/cm2 99.9% [58]