Kemeny 1999.

Methods	RCT
Participants	Colorectal cancer (CRC) metastatic to the liver eligible for resection
Interventions	LR (liver resection) + hepatic artery chemotherapy vs no hepatic artery therapy. Both groups received systemic chemotherapy
Outcomes	Overall survival (OS), Disease free survival (DFS), Hepatic resection FS, toxicity, surgical & catheter related adverse events,
Notes	Actuarial analysis supported the use of hepatic artery injection of adjuvant chemotherapy
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	High risk
Blinding? All outcomes	High risk
Blinding? All outcomes	High risk
Incomplete outcome data addressed? All outcomes	High risk