Table 2.
Linear association between E-DII and sex hormones.
| E-DII | TT | FT | E2 | FE2 | SHBG | TT/E2 |
|---|---|---|---|---|---|---|
| β (95%CI) | β (95%CI) | β (95%CI) | β (95%CI) | β (95%CI) | β (95%CI) | |
| Crude model† | ||||||
| Continues | 0.04 | 0.05 | 0.025 | 0.03 | -0.016 | 0.016 |
| (0.017, 0.066) | (0.028-0.077) | (-0.04, 0.09) | (-0.03, 0.09) | (-0.04, 0.007) | (-0.043, 0.078) | |
| Tertile 1 | Reference | Reference | Reference | Reference | Reference | Reference |
| Tertile 2 | 0.074 | 0.055 | -0.04 | -0.05 | 0.03 | 0.115 |
| (-0.05, 0.20) | (-0.08, 0.19) | (-0.24, 0.15) | (-0.25, 0.145) | (-0.08, 0.13) | (-0.11, 0.34) | |
| Tertile 3 | 0.194 | 0.21 | 0.12 | 0.126 | -0.03 | 0.07 |
| (0.06, 0.32) | (0.07, 0.34) | (-0.14, 0.38) | (-0.14, 0.39) | (-0.14, 0.08) | (-0.185, 0.33) | |
| P for trend | 0.015 | 0.008 | 0.34 | 0.28 | 0.68 | 0.59 |
| Adjusted model& | ||||||
| Continues | 0.035 | 0.026 | -0.03 | -0.036 | 0.012 | 0.065 |
| (0.007, 0.06) | (0.001, 0.05) | (-0.08, 0.02) | (-0.08, 0.01) | (-0.01, 0.03) | (0.02, 0.11) | |
| Tertile 1 | Reference | Reference | Reference | Reference | Reference | Reference |
| Tertile 2 | 0.056 | 0.005 | -0.14 | -0.17 | 0.074 | 0.197 |
| (-0.07, 0.185) | (-0.14, 0.15) | (-0.30, 0.024) | (-0.33, -0.008) | (-0.025, 0.17) | (0.0005, 0.39) | |
| Tertile 3 | 0.174 | 0.12 | -0.11 | -0.147 | 0.077 | 0.284 |
| (0.02, 0.325) | (0.034, 0.27) | (-0.315, 0.01) | (-0.35, 0.05) | (-0.02, 0.17) | (0.09, 0.47) | |
| P for trend | 0.07 | 0.15 | 0.28 | 0.15 | 0.23 | 0.04 |
E-DII, energy-adjusted dietary inflammation index; TT, total testosterone; FT, free testosterone; E2, estradiol; FE2, free estradiol; SHBG, sex hormone-binding globulin; TT/E2, the ratio of TT to E2.
E-DII tertile ranges: tertile 1, -5.04 to -0.69; tertile 2, -0.69 to 1.02; tertile 3, 1.02 to 4.55.
†Unadjusted.
&Adjusted for age, race, education, marital status, smoking, body mass index, waist circumference, type of menopause, time since menopause, parity, time of blood sampling and energy intake.
The numbers in bold letters indicate that the AIC was considered smaller. The numbers in bold letters indicate that the result was considered significant difference.