Table 11.

Correlations in DS cohort

Structure	Correlation with neuron number of:
	Structure volume	NFT number	NFT%
Entorhinal cortex—all layers	0.89***	−0.09	− 0.74***
Entorhinal cortex —islands	0.93***	0.25	− 0.89***
CA1	0.92***	− 0.01	− 0.76***
CA2	0.79***	− 0.44*	− 0.66***
CA3	0.80***	− 0.24	− 0.61***
CA4	0.41*	− 0.29	− 0.62***
Subiculum	0.92***	− 0.17	− 0.53***
Amygdala	0.60***	0.04	− 0.46***
Thalamus	0.53***	− 0.31	− 0.37
Substantia nigra	0.85***	− 0.06	− 0.41*
Magnocellular basal complex	0.85***	− 0.16	− 0.50**
CN	0.87***	− 0.20	− 0.38*
DN	0.22	0.28	− 0.15

*p < 0.05; **p < 0.01; ***p < 0.001