Table 2.

Correlations with age and dementia stage of structure volume, neuron number, NFTs number, NFT percentage and amyloid load (%)

Structure	Correlation with age of					Correlation with dementia stage of
	Structure volume	Neuron number	NFT number	NFT %	Amyloid load (%)	Structure volume	Neuron number	NFT number	NFT %	Amyloid load (%)
Entorhinal cortex – all layers	− 0.67***	−0.73***	0.40*	0.69***	0.10	−0.79***	− 0.80***	0.41*	0.76***	− 0.01
Entorhinal cortex − islands	−0.84***	− 0.78***	0.07	0.81***	−	−0.85***	− 0.84***	− 0.07	0.80***
CA1	−0.72***	− 0.80***	0.29	0.71***	0.33	−0.76***	− 0.84***	0.20	0.76***	0.40*
CA2	− 0.42*	− 0.59***	0.57**	0.56**	0.28	−0.60**	− 0.73***	0.45*	0.58**	0.51*
CA3	0.23	− 0.48**	0.57***	0.51**	0.26	−0.27	− 0.51***	0.69***	0.66***	0.38
CA4	− 0.22	− 0.55**	0.34	0.57**	0.34	−0.14	− 0.54**	0.40	0.71***	0.42*
Subiculum	0.69***	0.79***	0.46*	0.62***	0.28	−0.83***	− 0.86***	0.38	0.59**	0.27
Amygdala	− 0.49**	− 0.40*	0.46**	0.58***	0.04	−0.44*	− 0.55**	0.42*	0.52**	− 0.10
Thalamus	−0.58**	0.62***	0.53**	0.49*	0.50*	−0.49*	− 0.50*	0.33	0.42	0.44*
Substantia nigra	−0.72***	0.72***	0.25	0.42*	0.46*	−0.62**	− 0.66***	0.26	0.41	0.44*
Magnocellular basal complex	−0.53**	−0.63***	0.39*	0.46*	0.51**	−0.62**	− 0.70***	0.48*	0.61**	0.34
CN	−0.45**	−0.31	0.30	0.28	0.66***	−0.55**	− 0.52**	0.31	0.29	0.50*
DN	0.11	−0.04	− 0.46*	0.40	–	−0.08	− 0.03	0.72***	0.71***
Purkinje cells	–	−0.38	–	–	–		−0.31

^*p < 0.05; **p < 0.01; ***p < 0.001