Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 4;19:3. doi: 10.1186/s12974-021-02367-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 5 — Genetic ablation of microglia in Cx3cr1-iDTR mice does not cause brain parenchyma swelling or edema. A MRI measures of 3D parenchyma volume show no difference in genetic microglia ablated mouse brains compared to Cx3cr1-Cre or iDTR brains after Dtx treatment. B Water content does not change among Cx3cr1-Cre, Cx3cr1-iDTR or iDTR brains. C–H Diffusion parameters calculated from DTI data show no differences between microglia ablated (Cx3cr1-iDTR) and control (Cx3cr1-Cre) animals in striatum, cortex and corpus callosum. (Each data point represents an individual animal. Mean + SEM. No significant difference among any of the groups one-way or two-way ANOVA with Tukey post-hoc analysis). A and B data pooled from two independent experiments and C–H from a single experiment