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. 2022 Jan 5;22:15. doi: 10.1186/s12890-021-01799-7

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Identification of prognostic genes in the Freiburg cohort. (a) The intersection of genes between the DEGs and ferroptosis-related genes. (b) Heatmap plot of 19 prognostic DEGs. Red represents expression level of genes were up-regulated, blue represents expression level of genes were down-regulated. A relative color scheme uses the minimum and maximum values in each row to convert values to colors. (c) Forest plots of the univariate Cox regression analysis of the 19 prognostic DEGs. (d) A protein–protein interaction network for the 19 prognostic DEGs, 8 genes were excluded due to no connection with other genes