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. 2022 Jan 4;22:8. doi: 10.1186/s12866-021-02406-9

Fig. 1.

Fig. 1

A. Incidence of Diabetes. Five to – eight week old female NOD mice on a regular chow were administered P. histicola (dashed line, n = 23) or not (solid line, n = 15). Initial onset for the untreated group was 14 weeks of age and 16 weeks of age for the P. histicola treated group. The mean onset for the untreated was 21 weeks of age, and over 25 weeks of age for the treated group, which was significant (p = 0.03 Gray K-Sample). B . H&E staining of Pancreas. Hematoxylin and eosin stained pancreata from female NOD mice administered P. histicola for 3 weeks (9 weeks of age) were evaluated for inflammation on a score from 0 to 3. P. histicola treatment significantly decreased the inflammation of the pancreas score from a median of 2 to 1.5 (p < 0.01)