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. 2006 Oct 18;2006(4):CD003781. doi: 10.1002/14651858.CD003781.pub2

SerranoBrambila 2000.

Methods RCT. Placebo controlled, crossover design. 
 Double‐blind. 
 Masking of assessors not stated.
Participants 44 female patients. 
 Inclusion criteria: Unstable bladder.
Interventions Treatment 1: oxybutynin 5mg tid (n=22) 
 Treatment 2: placebo (n=22) 
 2 x 6 week treatments with one week washout between treatment periods.
Outcomes Symptom questionnaire (VAS). 
 Leakage episodes, frequency of micturition. 
 Residuals. 
 Urodynamic parameters. 
 Adverse events. 
 Laboratory tests.
Notes Translated from Spanish. 
 7 dropouts (treatment 1: 5, treatment 2: 2) 
 No follow up. 
 Data not in useable form for this review.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear