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. 2021 Nov;16(11):1704–1714. doi: 10.2215/CJN.03290321

Table 2.

Association of clamping time with delayed graft function

Characteristics N (%) Model Comparing am to pm Clamping
(for Midnight–Noon, n=1932;
for Noon–Midnight, n=947)
Model Comparing 6-h Time Periods of Clamping
(for Midnight–6 am, n=1135;
for 6 am–Noon, n=797;
for Noon–6 pm, n=360;
for 6 pm–Midnight, n=587)
Model Using 6 pm–Midnight as Reference
(for Midnight–6 pm, n=2292;
for 6 pm–Midnight, n=587)
Adjusted Odds Ratio (95% Confidence Interval) P Value Adjusted Odds Ratio (95% Confidence Interval) P Value Adjusted Odds Ratio (95% Confidence Interval) P Value
Time of clamping 0.03
 Noon–midnight 328 (35) 1 (ref)
 Midnight–noon 526 (27) 0.81 (0.67 to 0.98)
 6 pm–midnight 214 (36) 1 (ref) 0.15
 Midnight–6 am 325 (29) 0.77 (0.60 to 0.98)
 6 am–noon 201 (25) 0.77 (0.59 to 1.00)
 Noon–6 pm 114 (32) 0.85 (0.62 to 1.15)
 6 pm–midnight 214 (36) 1 (ref) 0.03
 Midnight–6 pm 640 (28) 0.78 (0.63 to 0.97)
Donor age, yr 1.01 (1.00 to 1.02) <0.001 1.01 (1.00 to 1.02) <0.001 1.01 (1.00 to 1.02) <0.001
Terminal donor serum creatinine (per 0.01 mg/dl) 1.01 (1.00 to 1.01) <0.001 1.01 (1.00 to 1.01) <0.001 1.01 (1.00 to 1.01) <0.001
Cause donor death 0.19 0.2 0.21
 Other 345 (28) 1 (ref) 1 (ref) 1 (ref)
 CVA 509 (31) 1.14 (0.94 to 1.38) 1.13 (0.93 to 1.38) 1.13 (0.93 to 1.38)
Donor CMV serology 0.22 0.24 0.24
 Negative 386 (32) 1 (ref) 1 (ref) 1 (ref)
 Positive 468 (28) 0.89 (0.74 to 1.07) 0.90 (0.75 to 1.08) 0.90 (0.75 to 1.08)
Sex 0.001 <0.001 0.002
 Female 268 (26) 1 (ref) 1 (ref) 1 (ref)
 Male 586 (32) 1.37 (1.13 to 1.65) 1.35 (1.12 to 1.64) 1.36 (1.12 to 1.64)
Recipient BMI, kg/m2 1.07 (1.05 to 1.09) <0.001 1.07 (1.05 to 1.10) <0.001 1.07 (1.05 to 1.10) <0.001
History of diabetes 0.3 0.3 0.30
 No 644 (28) 1 (ref) 1 (ref) 1 (ref)
 Yes 210 (34) 0.89 (0.71 to 1.11) 0.89 (0.71 to 1.11) 0.89 (0.71 to 1.11)
History of vascular disease 0.02 0.02 0.02
 No 653 (28) 1 (ref) 1 (ref) 1 (ref)
 Yes 201 (40) 1.32 (1.05 to 1.65) 1.32 (1.05 to 1.65) 1.31 (1.05 to 1.65)
History of cardiac disease 0.001 0.001 0.001
 No 522 (26) 1 (ref) 1 (ref) 1 (ref)
 Yes 332 (39) 1.39 (1.14 to 1.69) 1.38 (1.14 to 1.69) 1.39 (1.14 to 1.69)
Recipient blood group 0.03 0.02 0.07
 A 330 (27) 1 (ref) 1 (ref) 1 (ref)
 AB 45 (34) 1.29 (1.24 to 0.98) 1.31 (0.84 to 1.99) 1.31 (0.85 to 2.00)
 B 97 (29) 1.15 (0.85 to 1.54) 1.16 (0.86 to 1.56) 1.16 (0.86 to 1.56)
 O 382 (32) 1.33 (1.10 to 1.62) 1.33 (1.09 to 1.62) 1.33 (1.10 to 1.62)
HLA-A/-B/-DR incompatibilities ≥4 0.04 0.04 0.02
 No 403 (27) 1 (ref) 1 (ref) 1 (ref)
 Yes 451 (32) 1.30 (1.02 to 1.66) 1.30 (1.02 to 1.66) 1.24 (1.04 to 1.48)
Cold ischemia time, h 1.05 (1.02 to 1.06) <0.001 1.05 (1.03 to 1.06) <0.001 1.05 (1.03 to 1.06) <0.001

Total n=2879. ref, reference; CVA, cerebrovascular accident; CMV, cytomegalovirus; BMI, body mass index.