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Placebo-adjusted chronic yearly slopes from week 6 in the overall population and by baseline kidney function. Preservation of ≥0.75 ml/min per 1.73 m2 per year on eGFR slope predicts protection against CKD (9). Analysis was performed on the full analysis set. 95% CI, 95% confidence interval; KDIGO CKD, Kidney Disease Improving Global Outcomes in Chronic Kidney Disease; UACR, urinary albumin-to-creatinine ratio.
