TABLE 1.
Overview of antimicrobial peptides of the black soldier fly with in vitro verified antimicrobial activity
| AMP | AMP family | Study | Activity against | Strength of activity (MIC)a |
|---|---|---|---|---|
| DLP4 | Defensin | Park et al. (2015) | MRSAb S. aureus KCCM 40881 S. aureus KCCM 12256 S. epidermidis KCCM 35494 B. subtilis KCCM 11316 |
0.59 to 1.17 μM 0.59 to 1.17 μM 1.17 to 2.34 μM 0.59 to 1.17 μM 0.02 to 0.04 μM |
| Li et al. (2017) |
S. aureus ATCC 25923 S. aureus ATCC 43300 S. aureus ATCC 6538 S. aureus CICC 546 S. suis CVCC 606 L. ivanovii ATCC 19119 |
0.01 μM 0.23 μM 0.47 μM 0.47 μM 1.88 μM 0.12 μM |
||
| Li et al. (2020) |
S. aureus CVCC 546 S. epidermis ATCC 12228 S. pneumoniae CVCC 2350 S. suis CVCC 3928 |
3.75 μM 14.99 μM 7.50 μM 3.75 μM |
||
| DLP2 | Defensin | Li et al. (2017) |
S. aureus ATCC 25923 S. aureus ATCC 43300 S. aureus ATCC 6538 S. aureus CICC 546 S. suis CVCC 606 L. ivanovii ATCC 19119 |
0.01 μM 0.12 μM 0.12 μM 0.23 μM 0.93 μM 0.12 μM |
| DLP3 | Defensin | Park et al. (2017) |
MRSAb S. aureus KCCM 40881 S. aureus KCCM 12256 S. epidermis KCCM 25494 E. coli KCCM 11234 P. aeruginosa KCCM 11328 |
5 μg/mL 5 μg/mL 10 μg/mL 10 μg/mL 10 μg/mL 40 μg/mL |
| ID13 | Defensin | Li et al. (2020) |
S. aureus CVCC 546 S. epidermis ATCC 12228 S. pneumoniae CVCC 2350 S. suis CVCC 3928 |
0.95 μM 1.91 μM 0.95 μM 0.95 μM |
| CLP1 | Cecropin | Park et al. (2017) |
E. coli KCCM 11234 E. aerogenes KCCM 12177 P. aeruginosa KCCM 11328 |
0.52 to 1.03 μM 1.03 to 2.07 μM 1.03 to 2.07 μM |
| Trx-stomoxynZH1a | Cecropin | Elhag et al. 2016) |
E. coli
S. aureus |
15 to 30 μg/mL 27 to 54 μg/mL |
| HI-attacin | Attacin | Shin et al. (2019) |
E. coli KCCM 11234 MRSAb |
No MIC given No MIC given |
| HiCG13551 | IATP | Xu et al. (2020) |
E. coli
S. aureus S. pneumoniae |
No MIC given No MIC given No MIC given |
| Hidefensin-1 | Defensin | Xu et al. (2020) | E. coli | No MIC given |
| Hidiptericin-1 | Diptericin | Xu et al. (2020) |
E. coli
S. pneumoniae |
No MIC given No MIC given |
| Hill_BB_C6571 | Defensin | Moretta et al. (2020) | E. coli | No MIC given |
| Hill_ BB_C16634 | Defensin | Moretta et al. (2020) | E. coli | No MIC given |
| Hill_BB_C46948 | Defensin | Moretta et al. (2020) | E. coli | No MIC given |
| Hill_BB_C7985 | Defensin | Moretta et al. (2020) | E. coli | No MIC given |
a
MIC, minimum inhibitory concentration.
b
MRSA, methicillin-resistant Staphylococcus aureus.