TABLE 3.

IC₅₀ values (concentrations leading to 50% growth inhibition of the pathogen), MIC values (needed for visual absence of bacterial growth), and MBC values obtained in two individual screenings of the selected cecropins Hill-Cec1 and Hill-Cec10 performed at concentrations starting at 32 μM

		IC50 (μM)		MIC (μM)		MBC (μM)
Strain	Repeat	Hill-Cec1	Hill-Cec10	Hill-Cec1	Hill-Cec10	Hill-Cec1	Hill-Cec10
E. coli ATCC 8739	1	0.15	0.73	0.5	1	0.5	1
	2	0.15	0.63	0.25	1	0.25	32
P. aeruginosa ATCC 9027	1	0.64	0.75	1	1	1	8
	2	0.37	0.75	0.5	2	16	16
P. aeruginosa ATCC 15692 (PAO1)	1	0.77	2.48	1	8	4	16
	2	0.39	0.76	0.5	2	0.5	16
P. aeruginosa LMG 27650 (MDR)a	1	1.34	2.96	2	4	4	32
	2	0.66	3.35	1	8	16	16
P. aeruginosa ATCC 15442	1	0.73	2.82	1	4	4	16
	2	0.38	2.71	1	4	8	32
K. pneumoniae ATCC 13883	1	0.36	0.75	0.5	1	2	4
	2	0.18	0.31	0.25	0.5	4	8
B. cenocepacia LMG 16656	1	>32	>32	>32	>32
	2	>32	>32	>32	>32
M. tuberculosis ATCC 25177 (H37Ra)	1	>32	>32	>32	>32
	2	>32	>32	>32	>32

^aMDR, multi-drug-resistant.