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. 2021 Dec 22;12:787176. doi: 10.3389/fgene.2021.787176

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Copyright © 2021 Zhao, Cho and Nicolls.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Microbial alpha diversity comparisons in different groups and cohorts. Shannon’s diversity index (in y-axis) was used to measure alpha diversity for Kostic (A), Hale (B), Gao (C), Zeller (D), Burns (E), and Purcell (F). P0 groups were colored blue, P1 were colored red, and Normal were colored green. Alpha diversity differences between groups were evaluated using the pairwise Wilcoxon rank sum tests with Benjamini-Hochberg (BH) correction. Only statistically significant p-values (less than 0.05) were shown below the boxplots, and marked with star.