Figure 6.

Altered protein abundances in uEVs isolated from CA-SPAK mice are similar to those reported in the kidney. (A) uEVs were isolated from 24-hour urine and assessed by immunoblotting. Each lane represents uEVs isolated from a 24-hour collection period from the same mouse. (B) Summary data of relative abundances of uEV proteins in control and CA-SPAK mice. Data correlate well with relative abundances reported in the literature (see text). A single asterisk (*) denotes 0.01<P<0.05; a double asterisk (**) denotes 0.001<P<0.01, relative to control.