SARS-CoV-2 activates Type 1 IFN response in human kidney cells. (A) Box plots showing mean expression levels (log2[TPM+1]) of genes associated with the Gene Ontology term “response to type 1 IFN” (0034340) in Vero E6 cells, hKEpC, and kSPH from RNA-seq. These genes are downregulated in Vero E6 cells in comparison with their human counterparts, hKEpC and kSPH. (B) Representation of 15 genes showing the highest levels of expression in hKEpC, kSPH, and Vero E6 cells.